When is Metipred needed during pregnancy? "Metypred" during pregnancy: is it possible or not?

When carrying a child, a woman constantly needs to consult with 2 doctors: a gynecologist and an endocrinologist. The rest of the specialists, depending on the presence of certain pathologies, chronic diseases and other things. But keep an eye on general development child, the gynecologist must monitor exactly how the uterus enlarges and how the corresponding changes occur in the patient’s body.

But the endocrinologist looks at data on hormone levels. It depends on them how the body directly adapts, whether it can rebuild normally. After all increased amount male hormones are fraught late miscarriage or a frozen pregnancy. And if such a risk appears, immediate action must be taken.

If testosterone levels are increased, doctors may prescribe Metipred during pregnancy to normalize the situation. It's strong hormonal drug, which allows some women with the described problems to bear a child. But you need to drink it with great caution, only as prescribed by a specialist. And if you are not sure about your doctor, you should consult with other specialists.

Why so many precautions? The thing is that it is impossible to answer unequivocally whether it is possible to take Metipred during pregnancy: the risk here is very high. The medicine affects metabolic processes, suppresses the immune system, and affects the child. Therefore, it is prescribed only when all the nuances have been weighed and calculated. But let's figure out what this product is.

Composition and effect on the body

Basics active substance– methylprednisolone. It reduces inflammation and the body's immune response, resulting in the problem of allergic reactions being eliminated or becoming noticeably milder. This is balanced by the increased risks of catching ARVI during pregnancy, influenza, as well as exacerbation of the chronic disease, for example, herpes may begin to appear.

It interferes with a number of basic metabolic processes and inhibits the activity of the adrenal glands. Maximum activity in the body occurs a few hours after administration.

When is it shown?

The medicine is usually prescribed for serious autoimmune diseases, rheumatism, allergies, anaphylactic shock, a number of diseases of the lower respiratory tract, including asthma. It is prescribed for brain swelling caused by tumors and to suppress vomiting in patients receiving chemotherapy.

Thus, the instructions for use of Metipred say nothing about the treatment of any conditions during pregnancy. But it is stated directly that it should be used when carrying a child with great caution, solely based on vital signs.

The fact is that this hormone penetrates the placenta. It is capable of influencing the fetus. In addition, a woman is more likely to have a stillbirth. Therefore, when prescribing, there must be specific justification for the need for the medicine.

What do you need to know about admission?

The medicine is usually prescribed in tablet form, taken once a day with the required amount of water. The connection is based on the time of day - preferably in the morning after eating. In any case, the dosage of Metipred during pregnancy should be determined by a doctor, since there is a very wide range from 8 to 96 mg.

Please note that you should not suddenly stop taking it. And especially for those who are expecting a baby. A smooth exit with a gradual dose reduction is needed. IN otherwise Various negative consequences are possible.

As for how long they take the medicine, it’s hard to say. Often they start taking Metipred in the early stages to avoid miscarriage. Judging by the reviews, for many women this drug literally saved their children. And they drink it immediately before giving birth. That is, "Metypred" during pregnancy later won't surprise anyone. You can see it more clearly in the table.

As you can see, the medicine is prescribed to expectant mothers with great caution. But you need to carefully calculate all the risks and how justified such a decision is in principle.

Why is Metipred prescribed when planning pregnancy?

Doctors prescribe this medicine not only to those who have conceived, but also to those who are planning to have a child. Sometimes a long-awaited event never comes. And the reason here is increased testosterone. In this case, Metipred may be prescribed when planning pregnancy in order to normalize hormonal levels. But you should take it only strictly according to medical instructions.

Please note that the drug itself is often prescribed in combination to women who want a child. That is, when planning a pregnancy, Metipred and Duphaston are usually prescribed together, the first suppresses male hormones, the second normalizes the amount of female hormones. And together they accelerate the onset of the long-awaited conception.

Contraindications

In what cases should this medicine not be prescribed? The list is quite impressive.

Firstly, this is an intolerance to the components of the drug, please note that lactose is indicated here among the excipients.

Secondly if the patient has acute or chronic viral and bacterial infections, then Metipred is contraindicated because it suppresses the immune system.

Third, for mental disorders, and there are so many of them that even the manufacturers did not consider it necessary to list everything in detail in the instructions.

TO fourth group of contraindications include diseases of cardio-vascular system. It should not be taken by those who have diabetes, problems with the pancreas or with the gastrointestinal tract in general. Especially if there is a risk of gastric perforation.

Side effects

Side effects so many, so much so that a separate article could be devoted to them.

From the outside of cardio-vascular system There is a rhythm disturbance, failure, bradycardia up to complete cardiac arrest.

From the outside Gastrointestinal tract– peptic ulcers, perforation, the risk of the latter is especially high in the gallbladder.

From the outside psyche– depression, euphoria, paranoia, manic-depressive psychosis, exacerbation of schizophrenia, delirium and others. The drug is also quite harmful to the eyes and sensory organs in general. It changes hormonal levels and affects metabolic processes, may cause osteoporosis. Periodically provokes anaphylactic shock.

Combination with other drugs

The medication is considered very difficult in terms of combining it with other drugs. It’s really difficult to deal with, so even such a fairly common combination as “Metypred” with vitamins during pregnancy should be prescribed by a doctor. Cyclosporine, for example, can increase the toxicity of this drug. But there are also compounds that reduce the likelihood of side effects.

What can replace Metipred during pregnancy?

Many people are scared by Metipred, which is not surprising. Therefore, the question arises of selecting analogues. But if you choose, for example, “Metypred” or “Dexamethasone” during pregnancy, then the first one has at least such an advantage as imported origin. Many also believe that it is more easily accepted by the body.

But in general this is far from the only analogue. There are enough products on the pharmacological market containing prednisolone. And again, the doctor should find a replacement in any case!

When to stop Metipred during pregnancy?

It is important to understand not only when this medicine is prescribed, but when exactly it is discontinued. As a rule, in two cases: either the need for it has disappeared, the indicators have returned to normal, or the side effects are too strong, bad tests, the doctor began to worry about the woman’s health and life.

Let us remember that abrupt cessation of use can lead to very unpleasant consequences. For example, to adrenal insufficiency, which will already threaten the entire body. Therefore, it is necessary to reduce the dose gradually. And if access to the medicine is lost for some reason, urgently look for a replacement.

How does it affect the child?

As you might guess, the question of the drug’s effect on the fetus worries many mothers. Unfortunately, in this case there is reason to fear a negative development of the scenario. If you take Metipred during pregnancy, the consequences for the child can be very different.

The problem of lack of weight is common. There are cases when, after taking this drug, a baby was born with severe abnormalities, for example, 1.5 kilograms with normal period. In addition, some doctors suspect that the drug increases the risk of stillbirths.

Failures in the endocrine system of the fetus are possible, followed by problems with the thyroid gland and immune system. This remedy is especially negative for boys, since it suppresses male hormones in the mother’s body, which prevents the child from developing normally. Therefore, experts recommend that after receiving information about the baby’s gender, look for a replacement for such a medication.

Please note: not all of them are listed here. full list everyone potentially possible problems The child has. That is why the decision to take such a medicine should be made exclusively by an experienced, competent doctor.

How dangerous is the medicine really?

The instructions can scare anyone. The risks for the child are even more so. But in reality we are talking only about probabilities. There are plenty of examples where those who took this drug did not feel anything at all, they were born healthy children, although all previous attempts ended in failure.

Taking into account the fact that the drug is of imported origin, then if it brought more harm For what good, he would have been recalled long ago. But since this does not happen, it is obvious that in reality the picture is a little rosier.

It’s just that all cases are included in the instructions, even if we are talking about 1 person out of 1000. On the other hand, those who are “unlucky” will not be particularly interested in statistics. So you need to proceed carefully here.

Is it possible to make the situation easier?

As mentioned above, there are drugs that make Metipred less toxic to the body. Complex therapy will cost more, but the safety guarantees are worth it. Specific options can be selected together with the doctor leading the pregnancy.

And keep in mind that developments are now underway to create a more effective and safe analogue. New drugs regularly appear on the market. So don't be afraid to inquire about replacement options, even if no alternatives existed a few months ago. The situation is changing.

To summarize, it is worth noting that “Metypred” is effective, helps cope with elevated male hormones, eliminates inflammation and allergic reactions. This composition acts much softer than many domestic analogues. But at the same time, it is toxic to the body, suppresses the immune system, and has an impressive list of side effects. And it affects the fetus. Therefore, it is worth approaching the issue of taking it responsibly.

Everyone knows that it is undesirable to take medications when planning pregnancy and in its early stages. But sometimes pregnancy and its preservation are impossible without medical intervention. In this case, doctors prescribe metypred during pregnancy.

Metipred is prescribed when planning pregnancy and to maintain it. High level testosterone disrupts a woman’s hormonal levels, which can lead to a lack of ovulation and miscarriage. Metipred supports normal level hormones and possible pregnancy. But you should not stop taking the drug immediately. It is necessary to analyze the hormonal background, depending on it, continue or gradually stop using the product.

Metypred is used to accelerate the maturation of the epithelium and the onset of pregnancy. It is necessary for gynecological diseases requiring surgical intervention with organ removal.

In case of habitual abortions, metypred helps to cope with the problem. But you cannot take the medication without a doctor’s prescription. Disturbed hormonal levels will become even more unstable due to incorrect dosage - required amount determined individually.

If a woman was treated with metypred during pregnancy planning, and the instructions indicate that it is contraindicated for pregnant women, you should not stop taking the drug without consulting a specialist. An analysis of hormones alone becomes the decisive factor for cancellation.

Timely consultation with a doctor will protect you from the consequences recurrent miscarriage, will help you bear a healthy baby.

Effect of the drug

Metypred is a hormonal drug of synthetic origin. It has an immunosuppressive, anti-inflammatory, anti-allergic effect, normalizes the functioning of the adrenal glands, stabilizes hormonal levels and is responsible for the distribution of adipose tissue. Methylprednisolone is absorbed in 20 minutes, the half-life is 3 hours.

The drug is effective in the treatment of a number of connective tissue diseases, hypercalcemia, hypoglycemic conditions, hepatitis, ulcerative colitis, sclerosis, lung cancer, pneumonia, blood diseases, kidney diseases, cerebral edema, Quincke's edema, asthma, arthritis, rheumatism.

Note! A drug broad action, use without a doctor’s prescription is unacceptable.

Side effects

The use of metipred sometimes causes obesity, diabetes mellitus, stomach ulcers, nausea, vomiting, flatulence, arrhythmia, thrombosis, depression, increased blood pressure, blurred vision, and hypocalcemia. To monitor the condition, it is necessary to regularly take blood tests. An active lifestyle and a diet without excesses and harmful foods will help you maintain your health.

Side effects such as dizziness, nausea, and vomiting may be only the body’s first reaction. You need to inform your doctor about this, he will reduce the dosage.

Weight gain due to hormonal imbalance is difficult to avoid, but its normalization will occur after discontinuation of the medication. Metypred often has to be taken throughout the pregnancy, despite the contraindication; without it, pregnancy is impossible in some cases.

Significant weight gain during pregnancy is a stereotype; the gain depends on the initial indicator and the woman’s lifestyle.

Contraindications

Metypred is contraindicated in patients with glaucoma, osteoporosis, psychosis, renal failure, diseases of the cardiovascular system, immunodeficiency states, tuberculosis, herpes, smallpox, and gastrointestinal diseases.

The drug should not be taken on an empty stomach or immediately after meals, before bedtime, or at stressful situations. Pregnancy is stressful for the female body, hormonal levels change, mood swings appear, and emotional and physical sensitivity increases. Non-drug sedatives will help prevent depression. The selection is made by a leading specialist.

During pregnancy and lactation, the drug should be taken with caution and only in a situation greater benefit for the mother than possible harm to kid. Combining metipred with other medications is dangerous; for example, paracetamol should not be taken more than once every six hours.

It is important to follow the dosage and time of administration recommended by your doctor. Cancellation of the dose occurs with a gradual reduction in the amount of medication. Abrupt cessation of use may result in a risk of miscarriage or premature birth. Overdose leads to side effects, can be treated activated carbon

and gastric lavage.

Any changes in the body must be reported to your doctor.

Effect on the fetus Metipred is a hormonal medication with a high concentration in the blood. It enters the fetal system, affecting the functioning of the adrenal glands of the unborn child. Doctors prescribe metypred during pregnancy only in cases of extreme necessity; you cannot voluntarily refuse to take the drug. Consultation with several specialists will help dispel the patient’s doubts. The health of the unborn child depends not only on drug intervention, but also emotional state

mother.

In some cases, discontinuation of the drug is not possible. The effect on the fetus is not critical: it does not cause deformities or developmental pathologies. After the birth of a child, it is necessary to monitor the level of its hormones; the systems of newborn babies are very quickly restored and normalized as a result of timely treatment. Important to remember! The child's pediatrician should know about all medications taken by the mother during pregnancy and lactation. Metypred is not compatible with breastfeeding

, therefore its use is gradually stopped before childbirth. Pregnancy is far from best period

Metypred is a hormonal medicine based on the active substance methylprednisolone, which has anti-inflammatory, antiallergic, and immunosuppressive effects. Available in the form of tablets and powder for the preparation of solution for injection. The drug is very serious and has a number of contraindications, so the attending physician must approach treatment carefully, taking into account the patient’s existing health problems. In particular, the drug should be used with caution in case of liver failure. Pregnancy is also among the contraindications. However, in some cases, even during this period, a woman is prescribed Metipred. When does this happen?

As a rule, Metypred is prescribed to pregnant women when there is a threat of miscarriage. And often it has to be taken for almost the entire period. Especially if this drug helped a woman get pregnant, that is, she took Metypred at the stage. The medicine evens out hormonal levels expectant mother when male hormones predominate in her body (with hyperandrogenism). Although some experts believe that the prescription of Metipred (or other drugs from the glucocorticoid group) during pregnancy can only be justified if there is a reliable diagnosis of CDN (congenital dysfunction of the adrenal cortex).

In general, of course, the use of Metipred during pregnancy is extremely undesirable. Only a doctor should prescribe the drug and exclusively for health reasons (especially in the first trimester). Moreover, this should be a doctor whom you absolutely trust. After all, the list of possible side effects from this medicine is, to put it mildly, scary:

• from the outside endocrine system: decreased glucose tolerance, steroid diabetes mellitus, manifestation of latent diabetes mellitus, suppression of adrenal function, Itsenko-Cushing syndrome (moon-shaped face, pituitary-type obesity, hirsutism, increased blood pressure, dysmenorrhea, amenorrhea, muscle weakness, stretch marks), delayed sexual development in children;
• from the outside digestive system: nausea, vomiting, pancreatitis, steroid gastric ulcer and duodenum, erosive esophagitis, gastrointestinal bleeding, perforation of the gastrointestinal tract wall, loss of appetite, indigestion, flatulence, ; rarely - increased activity of liver transaminases and alkaline phosphatase;
• from the cardiovascular system: arrhythmias, bradycardia (up to cardiac arrest); in predisposed patients, development or increased severity of heart failure, ECG changes characteristic of hypokalemia, increased blood pressure, hypercoagulation, thrombosis; in patients with acute and subacute myocardial infarction, the necrosis focus may spread, the formation of scar tissue may slow down, which can lead to rupture of the heart muscle;
• from the central nervous system and peripheral nervous system: delirium, disorientation, euphoria, hallucinations, manic-depressive psychosis, depression, paranoia, increased intracranial pressure, nervousness, anxiety, insomnia, dizziness, vertigo, cerebellar pseudotumor, headache, convulsions;
• from the sensory organs: posterior subcapsular cataract, increased intraocular pressure with possible damage to the optic nerve, a tendency to develop secondary bacterial, fungal or viral infections of the eyes, trophic changes in the cornea, exophthalmos, sudden loss of vision (with parenteral administration in the head, neck, nasal shells, scalp, possible deposition of drug crystals in the vessels of the eye);
• on the metabolic side: increased calcium excretion, hypocalcemia, increased body weight, negative nitrogen balance (increased protein breakdown), increased sweating; caused by mineralocorticoid activity - fluid and sodium retention (peripheral edema), hypernatremia, hypokalemic syndrome (hypokalemia, arrhythmia, myalgia or muscle spasm, unusual weakness and fatigue);
• from the outside musculoskeletal system: slower growth and ossification processes in children (premature closure of the epiphyseal growth zones), osteoporosis (very rarely - pathological bone fractures, aseptic necrosis of the head of the humerus and femur), muscle tendon rupture, steroid myopathy, decreased muscle mass (atrophy);
• dermatological reactions: delayed wound healing, petechiae, ecchymosis, skin thinning, hyper- or hypopigmentation, steroid acne, stretch marks, tendency to develop pyoderma and candidiasis;
• allergic reactions: skin rash, itching, anaphylactic shock, local allergic reactions. Local reactions during parenteral administration: burning, numbness, pain, tingling at the injection site, infection of the injection site; rarely - necrosis of surrounding tissues, scar formation at the injection site, atrophy of the skin and subcutaneous tissue with intramuscular injection (injection into the deltoid muscle is especially dangerous);
• others: development or exacerbation of infections (the appearance of this side effect is facilitated by jointly used immunosuppressants and vaccination), leukocyturia, withdrawal syndrome, “flushes” of blood to the head.

The incidence and severity of side effects depends on the duration of use and the size of the dose used. Typically, pregnant women are prescribed a minimum of 0.5 tablets per day. With long-term use of the drug daily dose should be reduced gradually. Long-term therapy should not be stopped suddenly.

Be careful when combining Metypred with other medications. If you have been prescribed Metypred, check with your doctor or carefully study the instructions for the effects of it with other medications. Thus, with paracetamol it increases the risk of developing hepatotoxicity, and with vitamin D its effect on calcium absorption in the intestine is reduced. Metipred solution is also recommended to be administered separately from other drugs.

It is believed that especially dangerous use Metypreda may be for an unborn boy, since it especially affects the functioning of the fetal adrenal glands male. As a rule, children whose mothers were treated with this drug during pregnancy are fully examined after birth, especially the kidneys and adrenal glands. And in the West, Metypred is not used at all. But our doctors explain the use of this drug for pregnant women by the fact that this is often the only way to maintain the desired pregnancy. And in small doses, Metypred is generally safe for a pregnant woman and her unborn child, they assure.
Experience shows that many women who take Metipred throughout pregnancy have successfully given birth to healthy babies. But the annotations for the drug are still not encouraging. If you need to use Metipred, then find a competent specialist who will select the correct dosage for you and prescribe adequate treatment. And don't worry about anything. After all, sometimes you have to take risks to get what you want.

Especially for- Elena Kichak

Various negative factors, stress, poor environment can cause hormonal imbalances during pregnancy. This leads to problems with pregnancy, including miscarriage. To prevent dangerous situation Doctors prescribe the drug Metypred.

Composition and action

Metypred - hormonal medicine, which has an anti-inflammatory, anti-allergic effect, increases the body's immune strength.

The main active ingredient of the drug is methylprednisolone, which interacts with steroid hormone receptors in the blood cytoplasm. Thus, the synthesis of proteins and some enzymes involved in immune and inflammatory processes, as well as in the destruction of joints. The drug promotes the production of a special protein compound - lipocortin, which increases the body's ability to resist inflammation.

Interestingly, the anti-inflammatory effect of Metipred is 5 times higher than that of hydrocortisone (a hormone that affects protein and carbohydrate metabolism).

Forms of release of the drug

Metypred is available in several forms:

• tablets in dosages of 4 and 16 mg of methylprednisolone;
• lyophilized powder from which a solution for injections is prepared.

The maximum concentration of the active ingredient in the blood is achieved within 2 hours after taking the tablets, and with drip administration - after 15–20 minutes. The bioavailability of methylprednisolone is almost 80%. The substance is excreted by the kidneys.

Indications for prescribing the drug and its use during pregnancy

The main indications for prescribing the drug to expectant mothers are:

• a lack of female hormone progesterone;
• increased level male hormone testosterone;
• hyperandrogenism (excess of male hormones);
• threat of miscarriage, especially if spontaneous abortion happened before;
• polycystic ovary syndrome caused by adrenal dysfunction;
• detachment ovum which is caused by hormonal imbalance;
• pregnancy using IVF (in vitro fertilization).

Metypred promotes alignment hormonal levels, lowering testosterone production and increasing the amount of progesterone.

In addition, the medicine may be prescribed for:

• asthma and other diseases of the lower respiratory tract;
• allergic reactions, including anaphylactic or blood transfusion (caused by incompatibility of blood during transfusion) shock;
• acute hepatitis, which can cause hepatic coma;
• shock due to severe poisoning, injury, burn (if other drugs do not help);
• ulcerative colitis and Crohn's disease;
• multiple sclerosis;
• elevated intracranial pressure and cerebral edema;
• recovery after transplantation or chemotherapy.

How safe is Metypred for the fetus?

The instructions indicate that during pregnancy Metypred is prescribed for life. important indications. As a rule, medicine is prescribed only for early stages(in the first trimester). Women who are at risk of miscarriage due to hormonal imbalance, the drug is recommended to be taken over a long course, sometimes until delivery. If an IVF procedure has been performed, the need for therapy disappears by the middle of pregnancy.

Medical opinions are divided regarding the need to use Metipred. In most cases, the drug is prescribed for elevated level progesterone, or, more precisely, the 17-OPG (oxyprogesterone) indicator, which is extremely undesirable during pregnancy, as it can cause a miscarriage.

Today, endocrinologists view the increase in this hormone in women differently. The fact is that during pregnancy, an increase in oxyprogesterone is considered physiological norm. Therefore, treatment with Metipred is not advisable.

Admission rules

Metypred is often prescribed at the stage of pregnancy planning. Since the main purpose of the medicine is to preserve the fetus, it is often taken until birth. The duration of treatment depends on the indications, individual characteristics women.

As a rule, expectant mothers are prescribed tablets that should not be crushed or chewed. Take them whole in the morning, washed down big amount liquids. In other forms, the medicine is used only in severe cases. The dosage and duration of therapy are selected individually by the attending physician.

Stopping a medication like any other hormonal agent, occurs gradually. Quick withdrawal from Metipred can cause the following:

• stomach ache;
• joint weakness;
• headache;
• nausea;
• dizziness;
• increased body temperature;
• adrenal insufficiency.

In some cases, abrupt cessation of therapy leads to miscarriage.

Progesterone during pregnancy - video

Contraindications and possible adverse reactions

The drug is strictly prohibited when individual intolerance methylprednisolone or lactose, which is an auxiliary component of the tablets. In addition, the medicine is not prescribed to patients with identified chronic or acute viral/bacterial infections, latent or open tuberculosis in cases where these diseases are not treated.

Caution should be exercised when using the drug when:

• high blood pressure;
• diseases of the gastrointestinal tract;
• diabetes mellitus;
• tendency to form blood clots;
• heart failure;
• Itsenko-Cushing syndrome;
• eye diseases.

It should be borne in mind that Mutipred has the ability to suppress the immune system, so a pregnant woman must be careful not to contract an infection.

With long-term use of Metypred, mineralization may be impaired bone tissue, which can cause softening and destruction of bones. Therefore, it is necessary to pay close attention to your diet, increase the amount of foods rich in potassium, and, on the contrary, reduce sodium intake.

While taking the drug, it is sometimes observed whole line side effects. Their frequency and severity depend on the duration of therapy, dosage, as well as the characteristics of the female body. As a rule, the first manifestation of a negative reaction is an allergy in the form of skin rash and itching. When administered intramuscularly, a burning sensation may occur at the injection site.

Adverse reactions described in the instructions - table

Metypred and pregnancy with a boy: should the drug be discontinued?

Women who are expecting a boy should take the drug with extreme caution. The fact is that the medicine has negative impact on the functioning of the fetal adrenal glands. It is advisable to stop using Metypred before the 27th week of pregnancy, since at this time these organs in the unborn child begin to function, producing own hormones. After delivery, a thorough examination of the newborn's kidneys and adrenal glands is carried out.

Substitute medications that a doctor may prescribe

If a woman is pregnant with a boy or there are contraindications for taking Metipred, the attending physician can change the treatment tactics and select a medicine with a similar effect.

Metypred substitutes - table

Pregnancy is special condition female body. For successful completion complex process During the formation of the fetus and subsequent childbirth, a woman must take care of her health. Proper nutrition, good dream, good rest, moderate physical activity and a positive mood are her main helpers. Sometimes it is impossible to do without medical supplies, especially with hormonal surges.

Description of the drug

If the expectant mother has problems with hormones, then she may be prescribed Metipred. The drug belongs to the group of glucocorticosteroids and contains methylprednisolone. Entering female body, active substance The drug affects cytoplasmic receptors that are sensitive to steroids. This interaction leads to inhibition of the synthesis of cytokines and other enzymes, and the production of lipocortin increases.

Increased levels of lipocortin help reduce the rate of immune and inflammatory reactions and slow down the destruction of joints. Many times increasing the protective function immune system women, Metypred during pregnancy prevents allergic reactions and reduces the risk of edema. The drug is well absorbed from the gastrointestinal tract and retains its active action within 18–36 hours, almost completely eliminated from the body after 3 hours. Taking Metipred is possible only under the strict supervision of a doctor.

In what cases is the drug prescribed in preparation for conception and pregnancy?

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When carrying a child long reception Metypreda is not recommended. Accumulating in the mother's body, it active ingredients can cause intrauterine adrenal insufficiency in the baby. Abrupt withdrawal of medication during pregnancy is also prohibited. Discontinuation of hormonal therapy is carried out by gradual decline dosage of the drug, carried out under the constant supervision of a specialist.

To timely adjust daily doses of the drug, a woman must constantly donate blood for hormone analysis. Comparing the results obtained, the doctor sees how the level of hormones changes and wisely reduces the daily dose. IN general recommendations The use of Metipred states that it should not be taken on an empty stomach and should not be taken immediately after meals. The tablets should be taken with plenty of water.

Contraindications for use

The complex composition of Metypred and its hormonal nature for certain diagnoses can negatively affect the body of a pregnant woman. Manufacturers have included in the list of contraindications the following negative factors and diseases for which the drug is not prescribed:

• tuberculosis disease;
• individual intolerance to the components of the product;
• acute stage of a bacterial or viral disease;
• heart failure;
• hypertension;
• pancreatitis;
• diabetes.

The medicine should not be taken simultaneously with drugs such as Paracetamol or vitamin D. The interaction of Metipred with the first drug causes hepatotoxicity, and in the second case, calcium absorption by the intestines is reduced. Caution in taking the medicine is also observed when the patient has problems with blood clotting, a tendency to osteoporosis and thrombophlebitis is detected, and glaucoma is diagnosed.

Only circumstances that really threaten the life of the fetus force the doctor to resort to prescribing Metypred in the first trimester of pregnancy. The drug is prohibited for women during lactation, since glucocorticosteroids enter the breast milk emotional state

If pregnancy occurs as a result of in vitro fertilization, taking the medicine is allowed only as a last resort. At the same time, the practice of treatment with Metipred shows that the majority of women taking the drug gave birth to healthy children.

Analogues of the drug

Knowing about the large list of contraindications and side effects of Metipred, doctors are still inclined to prescribe it. The decision is made due to the fact that the benefits of the medicine outweigh the risk of manifestations side effects. If a pregnant woman’s body has a strong negative reaction to the drug, the doctor will replace it with some analogue. The best of them are shown in the table:

Metypred is a serious medical product and requires a competent approach to use. A pregnant woman should trust the doctor and strictly follow all his instructions. If you feel a clear deterioration in your condition after taking the product, tell your doctor immediately. Having bought Metypred at a pharmacy as prescribed by a doctor, do not be lazy to carefully study the instructions for it.